By A Mystery Man Writer
The double-helix structure of DNA is deformed by environmental stimuli, which will then affect gene expression, and eventually trigger a sequence of cellular processes. Recent research led by a physicist from City University of Hong Kong (CityU) observed substantial DNA deformations by ions and temperature changes. The researchers developed one simple physical model to explain DNA deformations. These results provide new insights into the molecular mechanisms of cellular responses to ions and temperature changes and can be used to control gene expression using ions and temperature.
Efficient modification and preparation of circular DNA for
Representative structures illustrate the structural diversity and
IJMS, Free Full-Text
Chapter 9: DNA Replication - Chemistry
Chromatinization modulates topoisomerase II processivity
The RNA polymerase II general transcription factor TFIIB is a
揭示DNA和RNA螺旋扭转改变的物理机制
Nucleic Acid Secondary Structure - an overview
Mechanisms of transcriptional regulation by DNA supercoiling. (A